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Medical Imaging: Whole Slide Imaging

Problem statement

One reason for differences in whole slide imaging is the lack of a suitable calibration process which means that the same slide can look very different from system to system

Proposal

Vendors that have worked in this area should pool their resources to develop a calibration system for digital microscopes

Participants

  • Organisations: ICC, DICOM WG26, FDA
  • Individuals:
Company / OrganisationName
FFEI Limited, ICCCraig Revie
GE OmnyxMichael Montalto
PhilipsBas Hulsken
Roche VentanaScott Forster
Leica / AperioAllen Olson
GE OmnyxVipul Baxi
NIH, NCIStephen Hewitt
FDAAldo Badano
FDAWei-Chung Cheng
GE OmnyxMichael Meissner
MGH / HarvardYukako Yagi
MGH / HarvardPinky Bautista
Leeds HospitalDarren Treanor
HamamatsuScott Blakely
Sakura FinetekMegumi Kondo
XRiteTom Lianza
3D HistechViktor Varga
XRiteTom Lianza
Tokyo Institute of TechnologyMasahiro Yamaguchi
Avian RochesterDave Wyble

Project coordinator: Craig Revie

Medical Imaging Working Group main page.


Meetings

15 January 2015 Calibration slide meeting | Minutes | Audio recording

25 September 2014 Calibration slide meeting | Minutes | Audio recording

20 June 2014 FDA Face-to-face meeting | Minutes | Audio recording

19 June 2014 Calibration slide meeting Minutes | Audio recording (incomplete recording)

3 Mar 2014 Working Group full meeting Minutes | Audio recording

20 February 2014 telecon Minutes | Audio recording

21 January 2014 telecon Minutes | Audio recording

9 December 2013 telecon Minutes | Audio recording

8 November 2013 telecon Minutes | Audio recording

9 October 2013 telecon Minutes | Audio recording

29 August 2013 telecon Minutes

See the Medical Imaging Working Group main page for details of upcoming meetings.

Documents

Colour calibration errors for an Ektachrome film calibration (03.08.2017)

draft Digital microscope test materials and test methods (v3: 26.11.2013)

draft Yagi digital microscope calibration

ICC review of draft FDA guidance on WSI devices | Audio recording of 23 April 2015 review meeting

FDA guidance on WSI devices The FDA published this guidance for Whole Slide Imaging Systems on April 20, 2016, with many MIWG comments adopted. Section IV(B)(1)(b), Test Methods points users to the ICC web site for references on the subject of color reproducibility. While there are many useful references on the web site, some areas are not covered completely and the ICC is considering providing additional details and suggestions. If there are any areas where you think additional information could be useful please contact Craig Revie or Phil Green.

Resources

DPA Whole Slide Imaging Repository This web page lists sources for whole slide and static image examples.

Virtual Display Color Processor code

Does the choice of display system influence perception and visibility of clinically relevant features in digital pathology images? Presentation by Tom Kimpe